ARTICLE NAME:

Comparative Analgesic and Antipyretic activity of ethanolic extract of Tragia involucrata

AUTHOR NAME

Kalaivanan M, L. Louis Jesudoss, A. Saravana Ganthi and M. Padma Sorna Subramanian

ISSUE:

VOL.1, NO.1

YEAR:

JUNE 2018

PAGE NO:

41-49

ABSTRACT:

The present study investigates the analgesic and antipyretic activity of ethanolic extract of Tragia involucrata, is a valuable medicinal plant. Phytochemical analysis of Tragia involucrata plant extracts revealed the presence of various bio-chemical compounds such as flavonoids, glycosides, alkaloids, saponins and terpenoids. Since flavonoids have remarkable analgesic activity, the present work aims at evaluating the in-vivo analgesic activity of Tragia involucrata by acetic-acid induced writhing response method and Eddy’s hot plate method. Brewer’s yeast induced hyperpyrexia method was used for antipyretic activity study. The data of the present studies suggests that T. involucrata extract showed significant anti-pyretic and analgesic activity. Therefore the present studies support the isolation and use of active constituents of Tragia involucrata in treating pain. Key Words: Tragia involucrata, flavanoids, analgesic activity, antipyretic activity

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